FEATURES OF THE POSTOPERATIVE PERIOD AFTER DENTAL IMPLANTATION ON THE BACKGROUND OF GENERALIZED PERIODONTITIS IN MILITARY SERVICEMEN

Abstract

Purpose of the study. To assess the role of immunological disorders and markers of endogenous intoxication syndrome in the development of inflammatory complications after dental implantation in patients with generalized periodontitis in the long-term clinical remission phase by a comprehensive study of the cytokine profile. Materials and methods of research. 67 military servicemen aged 35 to 52 were treated, who arrived at the dental clinic for intracystic dental implantation, of which 32 patients without tissue pathology periodontal disease and 35 patients with generalized periodontitis. Clinical, biochemical and immunological investigations carried out in the preoperative period made it possible to establish that the initiators of the inactive ignition process in the cervical tissues are responsible for the damage to the side of the body. functioning of the cytokine system, active ‒ improvement of the oxidative, antioxidant potential of the blood serum and immunological status. Research results and their discussion. It is shown above that standard surgical procedures, which may become stuck during the installation of implants, can be used in patients, molded and further absorbed negative immune and antioxidant effects. On the 2nd day after intracystic dental implantation, the operated patients showed a greater expression of changes in the parameters of proinflammatory cytokines, increased activity of peroxidation processes. IPids against the background of decreased antioxidant activity of the blood. The damage revealed after the operation was less unidirectional in nature, but was more pronounced in the case of active ignition complications in the wound area, and less in the case of inactive manifestations of peri-implantitis. Conclusions. 1.in relatively healthy individuals, an increase in the activity of pro – inflammatory and less anti-inflammatory cytokines plays a leading role in the pathogenesis of chronic, inactive perimlantitis in the early period after dental implantation. 2. the formation of acute (active) and chronic (inactive) forms of perimplantitis in the early postoperative period is associated with an increase in the processes of free radical lipid oxidation, a weakening of antioxidant protection and an imbalance in the functioning of the cytokine system, the severity of which clearly correlates with the clinical manifestations of the disease.